Mild treadmill exercise inhibits cartilage degeneration via macrophages in an osteoarthritis mouse model
Objective: We previously reported how treadmill exercise can suppress cartilage degeneration.Here, we examined the changes in macrophage dynamics in knee osteoarthritis (OA) during treadmill exercise and the effect of macrophage depletion.Design: OA mouse model, generated via anterior cruciate ligament transection (ACLT), was subjected to treadmill